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What does the Monroe-Kellie doctrine say about the contents of the cranial vault?

Brain, neurons and blood

Brain, blood and cerebrospinal fluid

The Monroe-Kellie doctrine states that the cranial vault contains three components: the brain, blood, and cerebrospinal fluid (CSF). This principle is significant in understanding the dynamics of intracranial pressure and the relationships among these three components. Any increase in one component must be compensated by a decrease in one or both of the other components to maintain stable intracranial pressure.

In clinical practice, especially in emergency and critical care situations, this doctrine helps guide interventions for conditions such as traumatic brain injury or hydrocephalus. Recognizing the balance among these elements is essential in assessing and managing patients with potential intracranial hypertension or other neurological emergencies. The inclusion of air or neurons in the other options does not align with the fundamental aspects of the Monroe-Kellie doctrine, as neither are valid components within the cranial vault under normal conditions.

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Cerebrospinal fluid, air and blood

Brain, blood and air

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