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Homeostasis in the body is primarily maintained when the supply of oxygen is sufficient to meet cellular demands. Oxygen is crucial for cellular metabolism, particularly in the production of adenosine triphosphate (ATP), which is the energy currency of cells. When cells receive adequate oxygen, they can efficiently perform their functions, maintain energy levels, and support overall bodily functions, contributing to a stable internal environment.

When oxygen supply is compromised, it can lead to anaerobic metabolism, which produces lactate and can result in metabolic acidosis. Elevated serum lactate levels reflect an imbalance in the metabolic state and indicate that homeostasis is not being maintained.

High carbon dioxide levels can also disrupt homeostasis, leading to respiratory acidosis, which further complicates the body's ability to maintain equilibrium.

Similarly, a decrease in heart rate might seem like a stable state, but it could indicate inadequate perfusion or a response to other factors that may not align with a stable internal environment. Therefore, the capacity for the body to maintain homeostasis is heavily reliant on having an adequate oxygen supply to support cellular activity.